Regulatory effects of statins on CCL2/CCR2 axis in cardiovascular diseases: new insight into pleiotropic effects of statins
CCL2 plays a major role in the pathogenesis of cardiovascular disorders. Down-regulation of CCL2 is proposed as one of the pleiotropic properties of statins. However, more investigations are required to elucidate which statin in what dose exerts a more potent effect on CCL2/CCR2 pathway.
Authors
- Sercan Karav (ORCID: https://orcid.org/0000-0003-4056-1673)
- Hanieh Gholamalizadeh (ORCID: https://orcid.org/0000-0002-2083-0963)
- Amirhossein Sahebkar (ORCID: https://orcid.org/0000-0002-8656-1444)
- Behzad Ensan
- Tannaz Jamialahmadi
Institutions
- Çanakkale Onsekiz Mart Üniversitesi (TR)
- Mashhad University of Medical Sciences (IR)
- Biotechnology Research Center (IR)
- Saveetha University (IN)
Publication Details
- Journal
- Journal of Inflammation
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12950-024-00420-y
- Citations
- 7
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 4.01