CT-assessed sarcopenia and immune-related adverse events in patients with lung cancer: A competing risk time-to-event analysis
CT-assessed sarcopenia is associated with a reduced risk of any irAEs in patients with lung cancer receiving ICIs, possibly because higher muscle mass enhances the host response to immunological stimulation. Recognizing sarcopenia as a predictive factor for irAEs is relevant for personalizing treatments.
Authors
- Erick Suazo-Zepeda (ORCID: https://orcid.org/0000-0003-1518-7405)
- Willemijn J Maas (ORCID: https://orcid.org/0000-0002-0792-7090)
- Marjolein A. Heuvelmans (ORCID: https://orcid.org/0000-0002-5712-4085)
- Alain R. Viddeleer (ORCID: https://orcid.org/0000-0002-3288-140X)
- Geertruida H. de Bock (ORCID: https://orcid.org/0000-0003-3104-4471)
- T. Jeroen N. Hiltermann (ORCID: https://orcid.org/0000-0002-0665-2160)
- Douwe Postmus (ORCID: https://orcid.org/0000-0002-9458-7038)
Institutions
- University Medical Center Groningen (NL)
Publication Details
- Journal
- Lung Cancer
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1016/j.lungcan.2024.108054
- Citations
- 4
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- European Commission
- Consejo Nacional de Ciencia y Tecnología
- Horizon 2020 Framework Programme
- HORIZON EUROPE European Research Council