Pulsatilla chinensis functions as a novel antihyperlipidemic agent by upregulating LDLR in an ERK-dependent manner
These findings demonstrated that PC acts as an antihypercholesterolemic agent by upregulating LDLR in an ERK-dependent manner and holds potential in the treatment of hypercholesterolemia.
Authors
- Chengmei Ma
- Kun Luo (ORCID: https://orcid.org/0000-0003-3835-8342)
- Juan Feng (ORCID: https://orcid.org/0000-0003-0174-4784)
- Reina Yao (ORCID: https://orcid.org/0000-0001-9535-9611)
- Qiuyan Jiang (ORCID: https://orcid.org/0000-0002-7205-6180)
- Weifang Song (ORCID: https://orcid.org/0000-0001-8143-6882)
- Zheng-han Di
- Ruijun Wang (ORCID: https://orcid.org/0000-0001-8778-8328)
- Lan Xie (ORCID: https://orcid.org/0000-0002-7236-6904)
Institutions
- Shanxi Medical University (CN)
- Shanxi Fenyang Hospital (CN)
- Shenzhen Technology University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s13020-024-01044-3
- Citations
- 1
- Primary Topic
- Phytochemical Studies and Bioactivities
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- National Natural Science Foundation of China
- Beijing Talents Fund