Pimozide Inhibits Type II but Not Type I Hair Cells in Chicken Embryo and Adult Mouse Vestibular Organs

While providing a possible explanation for the vestibular side effects of Pimozide in humans, its inhibitory action on mammalian hair cells might be of interest for the local treatment of vestibular disorders characterized by altered vestibular input, like Ménière's disease.

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Publication Details

Journal
Biomedicines
Published
2024-12-18
DOI
https://doi.org/10.3390/biomedicines12122879
Citations
2
Primary Topic
Hearing, Cochlea, Tinnitus, Genetics
Type
article
Field-Weighted Citation Impact
0.72
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article

Pimozide Inhibits Type II but Not Type I Hair Cells in Chicken Embryo and Adult Mouse Vestibular Organs

Giorgio Rispoli, Giancarlo Russo, Roberta Giunta, Giulia Cheli et al.
2 citations
Biomedicines
Hearing, Cochlea, Tinnitus, Genetics
0.72
article

Pimozide Inhibits Type II but Not Type I Hair Cells in Chicken Embryo and Adult Mouse Vestibular Organs

Giorgio Rispoli, Giancarlo Russo, Roberta Giunta, Giulia Cheli, Sergio Masetto
article en
2 citations

Abstract

While providing a possible explanation for the vestibular side effects of Pimozide in humans, its inhibitory action on mammalian hair cells might be of interest for the local treatment of vestibular disorders characterized by altered vestibular input, like Ménière's disease.

BiomedicinesVol. 12(12)
University of Ferrara (IT), University of Pavia (IT)
Good health and well-being
Openalex Percentile: Top 29%
Hearing, Cochlea, Tinnitus, Genetics
0.72
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Pimozide Inhibits Type II but Not Type I Hair Cells in Chicken Embryo and Adult Mouse Vestibular Organs — Giorgio Rispoli, Giancarlo Russo, et al. · Biomedicines (2024) | TGRS Research Map | TGRS