Cas12f1 gene drives propagate efficiently in herpesviruses and induce minimal resistance
Due to lower resistance and higher penetration, Cas12f1 gene drives could potentially supplant Cas9 gene drives for population control.
Authors
- Guanxiong Lei
- Tongwen Zhang (ORCID: https://orcid.org/0000-0002-4713-9320)
- Kai Jiao (ORCID: https://orcid.org/0000-0002-5415-9020)
- Xianying Zeng
- Qiaorui Yao
- Keyuan Lai
- H. Dai (ORCID: https://orcid.org/0000-0003-2377-5477)
- Zhuangjie Lin
Institutions
- Shenzhen Bioeasy Biotechnology (China) (CN)
- Shanghai Public Health Clinical Center (CN)
- Xiangnan University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Genome biology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13059-024-03455-9
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Guangdong Province
- Southern Medical University