Collagen type III formation but not degradation is associated with risk of kidney disease progression and mortality after acute kidney injury
Circulating PRO-C3, a biomarker of fibroblast activity, was prognostic for kidney disease progression and mortality when measured 1 year after an episode of AKI. Biomarkers of fibroblast activity may help patient stratification after an episode of AKI by identifying patients at higher risk of kidney disease progression.
Authors
- Federica Genovese (ORCID: https://orcid.org/0000-0003-1984-1881)
- M.A. Karsdal (ORCID: https://orcid.org/0000-0001-5026-8740)
- Nadja Sparding (ORCID: https://orcid.org/0000-0002-6979-0632)
- Nicholas M. Selby (ORCID: https://orcid.org/0000-0003-0351-8326)
Institutions
- University of Nottingham (GB)
- Nordic Bioscience (Denmark) (DK)
- University Hospitals of Derby and Burton NHS Foundation Trust (GB)
Publication Details
- Journal
- Clinical Kidney Journal
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1093/ckj/sfae413
- Citations
- 2
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.68