Efficacy and safety of azathioprine in patients with Cronkhite-Canada syndrome: a case series from Peking Union Medical College Hospital
Azathioprine might be a good alternative medication in CCS patients who are steroid dependent or intolerant, or need augmentation therapy. The adverse events should be closely monitored especially myelosuppression and the tests of TPMT and NUDT15 genotypes before therapy may be helpful for medication guidance.
Authors
- Lixin Jin
- C Y Ou (ORCID: https://orcid.org/0000-0002-8036-7317)
- Tianming Xu
- Shuang Liu (ORCID: https://orcid.org/0000-0002-8495-5562)
- Ji Li (ORCID: https://orcid.org/0000-0002-0285-2966)
- Qiushi Xu
- Jingnan Li (ORCID: https://orcid.org/0000-0002-9578-2580)
- Runfeng Zhang
- Yang Zhuo
- Gechong Ruan
- Xuemin Yan (ORCID: https://orcid.org/0009-0000-5876-0385)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- People’s Hospital of Rizhao (CN)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s40360-024-00825-8
- Citations
- 5
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.12
Funders
- Peking Union Medical College Hospital
- Peking Union Medical College