The effect of lysophosphatidic acid on myometrial contractility and the mRNA transcription of its receptors in the myometrium at different stages of endometrosis in mares
In the course of endometrosis in mares, a disruption in the myometrial mRNA transcription of LPARs has been observed. This is the first study to examine the impact of LPA on myometrial contractility at diffrent stage of endometrosis. However, it is essential to consider that multiple factors may contribute to this process. Alternations in contractile activity and changes in myometrial LPARs mRNA transcription may indicate impaired LPA-signaling mechanisms in equine myometrium during endometrosis.
Authors
- A.W. Jończyk (ORCID: https://orcid.org/0000-0002-6867-0823)
- Graça Ferreira‐Dias (ORCID: https://orcid.org/0000-0003-0622-6513)
- Anna Zuzanna Szóstek-Mioduchowska (ORCID: https://orcid.org/0000-0003-4204-1698)
- Dariusz J. Skarżyński (ORCID: https://orcid.org/0000-0001-9537-3560)
- K.K. Piotrowska-Tomala (ORCID: https://orcid.org/0000-0001-6989-9243)
- Michał Wróbel (ORCID: https://orcid.org/0000-0002-7812-2070)
- Takuo Hojo (ORCID: https://orcid.org/0000-0001-5233-7674)
- Ewa Monika Drzewiecka (ORCID: https://orcid.org/0000-0002-1328-0190)
Institutions
- University of Lisbon (PT)
- Kyushu Okinawa Agricultural Research Center (JP)
- InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences (PL)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s12917-024-04384-2
- Citations
- 1
- Primary Topic
- Reproductive Physiology in Livestock
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Narodowe Centrum Nauki
- Narodowa Agencja Wymiany Akademickiej