CMTM6 promotes hepatocellular carcinoma invasion and metastasis and tumor-associated neutrophil immunoinfiltration through the Wnt/β-catenin pathway
CMTM6 plays a pivotal role in the development and progression of hepatocellular carcinoma through regulation of the Wnt/β-catenin pathway via β-catenin. Moreover, CMTM6 demonstrates the capacity to promote immune infiltration of TANs in hepatocellular carcinoma tissues. Consequently, CMTM6 exhibits potential as both an early diagnostic marker and a novel therapeutic target for patients with hepatocellular carcinoma.
Authors
- Mamumaimaitijiang-Abula Yi
- Yongqiang Zhao (ORCID: https://orcid.org/0000-0001-8729-9583)
- Qing Tong (ORCID: https://orcid.org/0000-0003-1566-1090)
- Dong Yan
- Huan Yang (ORCID: https://orcid.org/0000-0003-4570-2228)
- Panpan Kong
- Huifang Liu (ORCID: https://orcid.org/0009-0002-3982-355X)
Institutions
- Xinjiang Medical University (CN)
- Fifth Affiliated Hospital of Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- Tumor Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s40001-024-02189-5
- Citations
- 1
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- Natural Science Foundation of Xinjiang