Inactivation of the conserved protease LonA increases production of xylanase and amylase in Bacillus subtilis
The combination of transcriptome and ribosome profiling offered important information to determine at which cellular level production bottlenecks occurred. This helped us to identify LonA protease as an important factor influencing enzyme production yields in B. subtilis.
Authors
- Mariah B.M.J. Kes (ORCID: https://orcid.org/0000-0002-4316-5783)
- Leendert W. Hamoen (ORCID: https://orcid.org/0000-0001-9251-1403)
- Biwen Wang (ORCID: https://orcid.org/0000-0003-4383-3902)
- Gaurav Dugar (ORCID: https://orcid.org/0000-0002-5678-3679)
- Joen Luirink (ORCID: https://orcid.org/0000-0001-8431-0804)
- Anna C. H. van den Berg van Saparoea
Institutions
- Centrum Wiskunde & Informatica (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12934-024-02616-6
- Citations
- 4
- Primary Topic
- Bacterial Genetics and Biotechnology
- Type
- article
- Field-Weighted Citation Impact
- 2.20
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek