CRIME-Q—a unifying tool for critical appraisal of methodological (technical) quality, quality of reporting and risk of bias in animal research

The Critical Appraisal of Methodological (technical) Quality, Quality of Reporting and Risk of Bias in Animal Research (CRIME-Q) tool unifies a broad spectrum of information (both unique items and items inspired by other methods) about the quality of reporting and methodological (technical) quality, and contains items from SYRCLE's risk of bias. The tool is intended for use in assessing overall study quality across multiple domains and items and is not, unlike other tools, restricted to any particular model or study design (whether interventional or noninterventional). It is also easy to apply when designing and conducting animal experiments to ensure proper reporting and design in terms of replicability, transparency, and validity.

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Institutions

Publication Details

Journal
BMC Medical Research Methodology
Published
2024-12-19
DOI
https://doi.org/10.1186/s12874-024-02413-0
Citations
6
Primary Topic
Animal testing and alternatives
Type
article
Field-Weighted Citation Impact
3.83

Funders

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article

CRIME-Q—a unifying tool for critical appraisal of methodological (technical) quality, quality of reporting and risk of bias in animal research

Tiit Illimar Mathiesen, Mikkel Schou Andersen, Birgitte Brinkmann Olsen, Christian Mawrin et al.
6 citations
BMC Medical Research Methodology
Animal testing and alternatives
3.83
article

CRIME-Q—a unifying tool for critical appraisal of methodological (technical) quality, quality of reporting and risk of bias in animal research

Tiit Illimar Mathiesen, Mikkel Schou Andersen, Birgitte Brinkmann Olsen, Christian Mawrin, Asger Sand Paludan‐Müller, Frantz Rom Poulsen, Mikkel Seremet Kofoed, Bo Halle, Christian Bonde Pedersen
article en
6 citations

Abstract

The Critical Appraisal of Methodological (technical) Quality, Quality of Reporting and Risk of Bias in Animal Research (CRIME-Q) tool unifies a broad spectrum of information (both unique items and items inspired by other methods) about the quality of reporting and methodological (technical) quality, and contains items from SYRCLE's risk of bias. The tool is intended for use in assessing overall study quality across multiple domains and items and is not, unlike other tools, restricted to any particular model or study design (whether interventional or noninterventional). It is also easy to apply when designing and conducting animal experiments to ensure proper reporting and design in terms of replicability, transparency, and validity.

BMC Medical Research MethodologyVol. 24(1)
University of Copenhagen (DK), University of Southern Denmark (DK), Odense University Hospital (DK), Rigshospitalet (DK), Karolinska Institutet (SE), Zealand University Hospital (DK), Cochrane (DK), Centre for Cosmology and Particle Physics Phenomenology (DK), Otto-von-Guericke-Universität Magdeburg (DE)
Syddansk Universitet
Openalex Percentile: Top 6%
Animal testing and alternatives
3.83
DOIOpen Access PDFOpenAlex
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