CircRNA-mediated heterogeneous ceRNA regulation mechanism in periodontitis and peri-implantitis
This study highlights a heterogeneous circRNA-mediated ceRNA regulatory mechanism in peri-implantitis and periodontitis, activating signaling pathways and regulating gene expression. Key findings including a detailed analysis of the transcriptional landscape and identification of unique molecular signatures, pathways and cellular components in gingival tissues, offering insights into the molecular differences between peri-implantitis and periodontitis. The study may contribute to the understanding of the pathological mechanisms of these diseases and may aid in the development of targeted therapies.
Authors
- Hailun Zhou (ORCID: https://orcid.org/0000-0002-8943-9129)
- Rong Xiang (ORCID: https://orcid.org/0000-0002-4775-4948)
- Yuanyuan Peng (ORCID: https://orcid.org/0000-0003-2852-1951)
- Li Tang (ORCID: https://orcid.org/0000-0001-5468-985X)
- Zhiyong Chen (ORCID: https://orcid.org/0000-0002-8932-329X)
- Wenjin Chen (ORCID: https://orcid.org/0009-0007-8511-7572)
- Wenxia Chen (ORCID: https://orcid.org/0000-0003-2241-8320)
Institutions
- Guangxi University (CN)
- Guangxi Medical University (CN)
- Guangxi Academy of Agricultural Science (CN)
- Guangxi Center for Disease Prevention and Control (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s40001-024-02153-3
- Citations
- 6
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- National Natural Science Foundation of China
- Division of Graduate Education