The effect of dexmedetomidine on acute kidney injury after elective major abdominal surgery : a retrospective single-center propensity score matched study
In this single-center retrospective propensity-matched study, we did not detect a significant overall difference in post-operative AKI rates between patients treated with or without dexmedetomidine during major abdominal surgery. However, though additional prospective data are needed, our study found that administering dexmedetomidine with a loading dose may be associated with lower rates of AKI, potentially indicating a renoprotective effect of loading-dose dexmedetomidine in this setting.
Authors
- Rong Luo (ORCID: https://orcid.org/0000-0002-8684-3652)
- Haibei Liu (ORCID: https://orcid.org/0009-0008-4626-8375)
- Wensheng Zhang (ORCID: https://orcid.org/0000-0002-4712-8656)
- Ling Ye (ORCID: https://orcid.org/0000-0002-7558-8940)
- Yujun Zhang (ORCID: https://orcid.org/0000-0003-0419-5397)
- Qian Liu (ORCID: https://orcid.org/0000-0003-2420-1395)
- Juan Tan (ORCID: https://orcid.org/0009-0004-0252-7540)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Third People's Hospital of Chengdu (CN)
Publication Details
- Journal
- BMC Anesthesiology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12871-024-02845-7
- Citations
- 6
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 2.04
Funders
- Sichuan University
- West China Hospital, Sichuan University