Optical coherence tomography in secondary progressive multiple sclerosis: cross-sectional and longitudinal exploratory analysis from the MS-SMART randomised controlled trial
In our cohort of people with SPMS and long disease duration, OCT measures correlated with SDMT and deep grey matter volume at baseline; EDSS, T25FW and whole brain volume change at follow-up.
Authors
- Christopher John Weir (ORCID: https://orcid.org/0000-0002-6494-4903)
- Jeremy Chataway (ORCID: https://orcid.org/0000-0001-7286-6901)
- Ahmed Toosy (ORCID: https://orcid.org/0000-0002-4441-3750)
- Anisha Doshi (ORCID: https://orcid.org/0000-0001-6699-8668)
- Domenico Plantone (ORCID: https://orcid.org/0000-0001-6666-7244)
- Nevin John (ORCID: https://orcid.org/0000-0002-9834-4498)
- Jonathan Stutters (ORCID: https://orcid.org/0000-0002-9151-0844)
- Floriana De Angelis (ORCID: https://orcid.org/0000-0002-9833-1435)
- Arman Eshaghi (ORCID: https://orcid.org/0000-0002-6652-3512)
- Siddharthan Chandran (ORCID: https://orcid.org/0000-0001-6827-1593)
- Frederik Barkhof (ORCID: https://orcid.org/0000-0003-3543-3706)
- Alberto Calvi (ORCID: https://orcid.org/0000-0002-1953-2803)
- Richard Anthony Parker (ORCID: https://orcid.org/0000-0002-2658-5022)
- Thomas Williams (ORCID: https://orcid.org/0000-0002-8724-4678)
- Peter Connick (ORCID: https://orcid.org/0000-0002-3892-8037)
- David MacManus (ORCID: https://orcid.org/0000-0002-0902-977X)
- James R. Cameron (ORCID: https://orcid.org/0000-0003-0080-2786)
Institutions
- University of Siena (IT)
- Queen Mary University of London (GB)
- Australian Regenerative Medicine Institute (AU)
- National Institute for Health and Care Research (GB)
- UCL Biomedical Research Centre (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- Fundació Clínic per a la Recerca Biomèdica (ES)
- University College London (GB)
- Monash University (AU)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- University of Edinburgh (GB)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1136/jnnp-2024-334801
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Sanofi
- Queen Mary University of London
- NHS Greater Glasgow and Clyde
- National Institute for Health and Care Research
- University of Warwick
- Imperial College London
- Imperial College Healthcare NHS Trust
- University College London
- University of Oxford
- University of Leeds
- Rosetrees Trust
- University of Nottingham
- University of Sussex
- University of Edinburgh
- Oxford University Hospitals NHS Foundation Trust
- University College London Hospitals NHS Foundation Trust
- Sheffield Teaching Hospitals NHS Foundation Trust
- Barts Health NHS Trust
- Medical Research Council
- Efficacy and Mechanism Evaluation Programme
- Warwick Medical School