Potential cardioprotective effect of paroxetine against ventricular remodeling in an animal model of myocardial infarction: a comparative study
The current findings suggest that pre-treatment with paroxetine may exert a beneficial effect that protects against post-MI remodeling, including modulating fibrotic, inflammatory, and angiogenesis-related factors. Therefore, the current findings show the promising role of paroxetine as a cardioprotective that attenuates post-MI remodeling processes.
Authors
- Nouf Mohamed Al-Rasheed (ORCID: https://orcid.org/0000-0001-5283-1576)
- Anfal F. Bin Dayel (ORCID: https://orcid.org/0000-0002-7138-414X)
- Ahmad Almotairi
- Tahani K. Alshammari
- Asma S. Alonazi (ORCID: https://orcid.org/0000-0003-3367-002X)
- Maha F. El‐Tohamy (ORCID: https://orcid.org/0000-0001-9793-7761)
- Maha Abdulrahman Alamin (ORCID: https://orcid.org/0000-0002-4847-0840)
- Hana Alharbi (ORCID: https://orcid.org/0000-0002-6139-2816)
- Rehab Ali (ORCID: https://orcid.org/0000-0002-9434-1281)
- Sara Almodawah
- Rana Aldigi
Institutions
- King Saud University (SA)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s40360-024-00824-9
- Citations
- 3
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 1.21