Increased IDO expression and regulatory T cells in acute myeloid leukemia: implications for immune escape and therapeutic targeting
IDO inhibition using novel IDO inhibitors along with chemotherapy is a promising approach to overcome the immune escape mechanisms in patients with AML, who exhibit increased levels of IDO expression and Tregs.
Authors
- Behzad Poopak
- Ahmad Majd (ORCID: https://orcid.org/0000-0003-3707-7581)
- Raziyeh Hakak
Institutions
- Islamic Azad University North Tehran Branch (IR)
- Iran Khodro (Iran) (IR)
Publication Details
- Journal
- Blood Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1007/s44313-024-00048-0
- Citations
- 6
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.94