Integrated lipidomics and RNA-seq reveal prognostic biomarkers in well-differentiated and dedifferentiated retroperitoneal liposarcoma
Our study reveals different lipid metabolism, several transcriptional pathways between WDLPS and DDLPS, and examines several serum markers associated with the prognosis of RLPS. These findings provide a vital basis for future endeavors in diagnosing and predicting the prognosis of retroperitoneal liposarcoma with different differentiations.
Authors
- Bonan Liu (ORCID: https://orcid.org/0000-0002-9430-9935)
- Yan Liang (ORCID: https://orcid.org/0000-0002-8536-5951)
- Dao-Ning Liu (ORCID: https://orcid.org/0000-0003-3287-5592)
- Ang Lv (ORCID: https://orcid.org/0000-0003-0604-7232)
- Rongze Sun
- Cheng‐Peng Li (ORCID: https://orcid.org/0000-0002-6798-9541)
- Yan Wu (ORCID: https://orcid.org/0000-0002-2355-0887)
- Guoqiang Xue
- Hui Qiu (ORCID: https://orcid.org/0000-0002-5819-0965)
- Xiaoya Guan (ORCID: https://orcid.org/0000-0002-2621-5283)
- Chunyi Hao (ORCID: https://orcid.org/0000-0002-1233-1689)
- Qiao Liu (ORCID: https://orcid.org/0000-0002-6620-1994)
- Hongtao Zhang (ORCID: https://orcid.org/0000-0003-2058-8238)
- Jianhui Wu (ORCID: https://orcid.org/0000-0001-8741-3569)
- Zhen Wang (ORCID: https://orcid.org/0000-0002-6401-4968)
- Xiaopeng Wang (ORCID: https://orcid.org/0000-0002-4220-8737)
- Weiwei Jia (ORCID: https://orcid.org/0009-0009-7485-8679)
- Jingjing Ye (ORCID: https://orcid.org/0009-0000-8906-4454)
- Xiuyun Tian (ORCID: https://orcid.org/0000-0001-9953-2055)
- Shuquan Li (ORCID: https://orcid.org/0000-0003-2183-8489)
Institutions
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Changchun Obstetrics and Gynecology Hospital (CN)
- Peking University People's Hospital (CN)
- Ministry of Education (ET)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12935-024-03585-x
- Citations
- 2
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Peking University
- Beijing Municipal Administration of Hospitals
- Beijing Municipal Natural Science Foundation
- Peking University Health Science Center