Enantioselective synthesis of α-chiral sulfonates through palladium-catalyzed Tsuji–Trost sulfonylation with sulfur dioxide
We present a novel palladium-catalyzed asymmetric Tsuji–Trost reaction featuring sulfur dioxide insertion through a palladium-sulfonyl intermediate. This method yields α-chiral sulfonates with high efficiency and excellent enantioselectivities.
Authors
- X. He (ORCID: https://orcid.org/0000-0002-5534-6039)
- Zhong Lian (ORCID: https://orcid.org/0000-0003-2533-3066)
- Zhiqian Chang
- Fei Zhou (ORCID: https://orcid.org/0000-0003-1216-2181)
- Qingqing Wang (ORCID: https://orcid.org/0000-0002-7810-0293)
- Xiaohong Wang (ORCID: https://orcid.org/0000-0001-8465-9782)
- Xuemei Zhang (ORCID: https://orcid.org/0000-0002-3912-5295)
Institutions
- Sichuan University (CN)
- State Key Laboratory of Biotherapy
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1039/d4qo01887g
- Citations
- 9
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 2.25