<i>GLP-1R</i> Gene Polymorphisms and Metabolic Traits During Childhood and Adolescence: The EPOCH Study
GLP-1R polymorphisms are associated with faster BMI growth across development, and lower estimated insulin sensitivity and higher compensatory insulin secretion during adolescence. GLP-1R polymorphisms should be considered in future pediatric studies of genetic susceptibility for obesity and diabetes.
Authors
- Deborah H. Glueck (ORCID: https://orcid.org/0000-0003-0047-8939)
- Wei Perng (ORCID: https://orcid.org/0000-0001-8552-6850)
- Elizabeth Litkowski (ORCID: https://orcid.org/0000-0002-7079-696X)
- Lauren A. Vanderlinden (ORCID: https://orcid.org/0000-0002-4019-8395)
- Iain R. Konigsberg (ORCID: https://orcid.org/0000-0001-7356-100X)
- Melanie Cree‐Green (ORCID: https://orcid.org/0000-0003-1593-1695)
- Kylie K. Harrall (ORCID: https://orcid.org/0000-0003-4467-2282)
- Dana Dabelea (ORCID: https://orcid.org/0000-0001-9514-8929)
- Leslie A. Lange (ORCID: https://orcid.org/0000-0002-4220-6766)
Institutions
- Colorado School of Public Health (US)
- University of Michigan (US)
- University of Florida Health (US)
- Michigan Medicine (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1210/clinem/dgae880
- Citations
- 2
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.72