Outcomes of definitive radiotherapy vs. laryngectomy followed by adjuvant radiotherapy in patients with locally advanced laryngeal squamous cell carcinoma: real-world experience in a referral cancer center
Our analysis suggests that definitive radiotherapy in laryngeal cancer does not lead to a poorer outcome than total laryngectomy followed by adjuvant radiotherapy. In T4 patients, our findings should reassure clinicians and patients about the viability of definitive radiotherapy as a treatment approach.
Authors
- Borna Farazmand
- Ebrahim Esmati (ORCID: https://orcid.org/0000-0003-0555-4275)
- Kaveh Zakeri (ORCID: https://orcid.org/0000-0003-3921-480X)
- Farrokh Heidari (ORCID: https://orcid.org/0000-0002-6904-5691)
- Reza Ghalehtaki (ORCID: https://orcid.org/0000-0003-1162-2019)
- Mahdieh Razmkhah
- Maryam Taherioun
- Reyhaneh Bayani (ORCID: https://orcid.org/0000-0003-0672-810X)
- Niloufar Saeedi (ORCID: https://orcid.org/0000-0003-0113-5479)
- Ali Kazemian (ORCID: https://orcid.org/0000-0002-4500-4801)
- Nima Mousavi-Darzikolaee
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- Motamed Cancer Institute (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Radiation Oncology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13014-024-02565-9
- Citations
- 4
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.32
Funders
- Tehran University of Medical Sciences and Health Services