Immune modulation of buffalo peripheral blood mononuclear cells by two asparaginyl endopeptidases from Fasciola gigantica
rFgLGMN-1 and rFgLGMN-2 modulate several cellular and immunological functions of PBMCs, and exhibited distinct regulatory effects on these in vitro, which indicated that they may play roles in immune modulation and facilitate fluke development. However, due to uncertainties associated with in vitro experiments, further studies are necessary to elucidate the precise functions of these legumains.
Authors
- Wenda Di (ORCID: https://orcid.org/0000-0003-1037-0286)
- Yanfeng Guo (ORCID: https://orcid.org/0009-0001-1171-7897)
- Yu Zou (ORCID: https://orcid.org/0000-0002-8812-5662)
- Xiaoting Tang (ORCID: https://orcid.org/0000-0001-8971-3119)
- Weiyu Zhang
- Dongqi Wu
Institutions
- Guangxi University (CN)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13071-024-06570-5
- Primary Topic
- Helminth infection and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region
- National Natural Science Foundation of China
- Natural Science Foundation of Guangxi Province