Characterization of neuronal oscillations in the prelimbic cortex, nucleus accumbens and CA1 hippocampus during object retrieval task in rats predisposed to early life stress

In summary, a reduced synchronization between the PL, NAc, and CA1 during the object retrieval task indicates how early MS stress during a critical developmental period impacts the limbic circuit connectivity. This corresponded with enhanced curiosity index in adolescent MS rats, predicting an altered intrinsic motivation and hence a higher susceptibility to substance use disorders during adolescence.