Antimicrobial peptide production with Corynebacterium glutamicum on lignocellulosic side streams

For pediocin PA-1 production on lignocellulosic residues, extended batch cultivation was identified as the optimal process mode, producing up to <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mo>≃</mml:mo></mml:math> 104 mg/L active pediocin PA-1. Moreover, the production of pediocin PA-1 on this sustainable second generation resource exceeded its state-of-the-art production on yeast extract-based media <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mo>≃</mml:mo></mml:math> 1.5-fold.