Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma
The combination of stabilization of fracture-prone lesions, stimulation of bone healing, and anti-tumor effect suggest clinical testing of sicXer and boXer as part of a combined systemic/local treatment strategy in multiple myeloma and non-malignant diseases.
Authors
- Eline Menu (ORCID: https://orcid.org/0000-0002-0805-6581)
- Dirk Hose (ORCID: https://orcid.org/0000-0003-0806-5223)
- Thaqif El Khassawna (ORCID: https://orcid.org/0000-0002-1187-8578)
- Marian Kampschulte
- Karin Vanderkerken (ORCID: https://orcid.org/0000-0002-2137-7179)
- Jürgen Burhenne (ORCID: https://orcid.org/0000-0002-2190-1698)
- Marcus Rohnke (ORCID: https://orcid.org/0000-0002-8867-950X)
- Anja Seckinger (ORCID: https://orcid.org/0000-0002-2771-712X)
- Susanne Beck (ORCID: https://orcid.org/0000-0002-2652-8722)
- Daniel Zahner
- Elke De Bruyne (ORCID: https://orcid.org/0000-0003-4012-4617)
- Francisca Alagboso
- Michael Gelinsky (ORCID: https://orcid.org/0000-0001-9075-5121)
- Sabine Wenisch
- Reinhard Schnettler
- Volker Alt (ORCID: https://orcid.org/0000-0003-0208-4650)
- Ulrich Thormann (ORCID: https://orcid.org/0000-0002-8935-4731)
- Seemun Ray
- Christian Heiß (ORCID: https://orcid.org/0000-0002-3212-8995)
- J Bamberger
- Kim De Veirman (ORCID: https://orcid.org/0000-0002-1313-6121)
- Anja Henß (ORCID: https://orcid.org/0000-0001-5009-6512)
- Sina Rößler (ORCID: https://orcid.org/0000-0002-3506-0455)
- Thomas Hanke (ORCID: https://orcid.org/0000-0001-7202-9468)
- Anne Hild
- Martina Emde-Rajaratnam
Institutions
- Vrije Universiteit Brussel (BE)
- Justus-Liebig-Universität Gießen (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- University Hospital Regensburg (DE)
- Max Bergmann Zentrum für Biomaterialien (DE)
- Technische Universität Dresden (DE)
Publication Details
- Journal
- Journal of Hematology & Oncology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13045-024-01636-4
- Citations
- 3
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- Deutsche Forschungsgemeinschaft
- Universitätsklinikum Regensburg