Metabolizable alloy clusters assemble nanoinhibitor for enhanced radiotherapy of tumor by hypoxia alleviation and intracellular PD-L1 restraint
In conclusion, the therapeutic outcome supports the high-efficiency of radiotherapy based on BMS@Pt<sub>2</sub>Au<sub>4</sub> NPs in hypoxic tumors expressing PD-L1.
Authors
- Hongying Lv
- Rui Zhang (ORCID: https://orcid.org/0000-0003-2398-8309)
- Mengchao Jia
- Xiangshan Yang (ORCID: https://orcid.org/0000-0003-1903-1926)
- Shengnan Liu (ORCID: https://orcid.org/0000-0001-9886-068X)
- Juan Li (ORCID: https://orcid.org/0000-0003-1965-4576)
- Guanwen Ding
Institutions
- Jilin University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s12951-024-03057-4
- Citations
- 2
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.37
Funders
- Natural Science Foundation of Jilin Province
- Jilin University