Advancing diagnosis and early risk assessment of preeclampsia through noninvasive cell-free DNA methylation profiling
This study offers valuable insights into methylation changes at specific genomic regions throughout pregnancy, revealing critical differences between normal and complicated pregnancies. The power of noninvasive cfDNA methylation profiling was successfully proven, suggesting the potential to integrate this noninvasive approach into routine prenatal care.
Authors
- Machteld Baetens (ORCID: https://orcid.org/0000-0001-7573-1164)
- Bram Van Gaever
- Nico Callewaert (ORCID: https://orcid.org/0000-0003-2069-6917)
- Kristien Roelens (ORCID: https://orcid.org/0000-0003-0973-7554)
- Andries De Koker (ORCID: https://orcid.org/0000-0003-3939-7650)
- Leander Meuris (ORCID: https://orcid.org/0000-0001-8940-3022)
- Isabelle Dehaene (ORCID: https://orcid.org/0000-0002-4826-6946)
- Jo Van Dorpe (ORCID: https://orcid.org/0000-0001-8175-2930)
- Ellen Roets (ORCID: https://orcid.org/0000-0003-2315-614X)
- Björn Menten (ORCID: https://orcid.org/0000-0001-8182-659X)
- Sandra Janssens (ORCID: https://orcid.org/0000-0001-7262-3715)
- Stephanie Deblaere
Institutions
- Ghent University Hospital (BE)
- Ghent University (BE)
- VIB-UGent Center for Medical Biotechnology (BE)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13148-024-01798-5
- Citations
- 10
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 5.24