Lhx2 specifically expressed in HSCs promotes liver regeneration and inhibits liver fibrosis
We demonstrated that Lhx2 had pro-regenerative and antifibrogenic functions, and elucidated its regulatory mechanism. The study provided a potential target with dual effects for treating liver diseases.
Authors
- Jiawang Tao (ORCID: https://orcid.org/0000-0002-7905-5594)
- Shengxian Yuan (ORCID: https://orcid.org/0000-0002-4883-0156)
- Yinxiong Li (ORCID: https://orcid.org/0000-0002-8802-7720)
- Fan Jiang (ORCID: https://orcid.org/0000-0002-9727-853X)
- Lin Guo (ORCID: https://orcid.org/0000-0001-5698-270X)
- Jiongliang Wang
- Guangqi Zhou
- Yanran Liang (ORCID: https://orcid.org/0009-0009-7288-5059)
- Sunan Huang
- Zichao Wu (ORCID: https://orcid.org/0000-0003-2858-4856)
- Miaoxiu Tang
- Jie Wang (ORCID: https://orcid.org/0000-0003-2031-7227)
Institutions
- Second Military Medical University (CN)
- Chinese Academy of Sciences (CN)
- Guangzhou Institutes of Biomedicine and Health (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
- State Key Laboratory of Respiratory Disease (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Hepatology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1097/hep.0000000000001201
- Citations
- 14
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 5.17