Once-weekly semaglutide doubles the five-year risk of nonarteritic anterior ischemic optic neuropathy in a Danish cohort of 424,152 persons with type 2 diabetes

During five years of observation of all persons with T2D in Denmark, use of once-weekly semaglutide independently more than doubled the risk of NAION. Given the irreversible nature of NAION, it is important to acknowledge this risk, and upcoming studies should aim to identify high-risk subgroups.

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Publication Details

Journal
International Journal of Retina and Vitreous
Published
2024-12-18
DOI
https://doi.org/10.1186/s40942-024-00620-x
Citations
51
Primary Topic
Intraoperative Neuromonitoring and Anesthetic Effects
Type
article
Field-Weighted Citation Impact
29.21
Controls
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article

Once-weekly semaglutide doubles the five-year risk of nonarteritic anterior ischemic optic neuropathy in a Danish cohort of 424,152 persons with type 2 diabetes

Jakob Grauslund, Ryo Kawasaki, Kurt Højlund, Laleh Dehghani Molander et al.
51 citations
International Journal of Retina and Vitreous
Intraoperative Neuromonitoring and Anesthetic Effects
29.21
article

Once-weekly semaglutide doubles the five-year risk of nonarteritic anterior ischemic optic neuropathy in a Danish cohort of 424,152 persons with type 2 diabetes

Jakob Grauslund, Ryo Kawasaki, Kurt Højlund, Laleh Dehghani Molander, Sören Möller, Andreas Abou Taha, Lonny Stokholm
article en
51 citations

Abstract

During five years of observation of all persons with T2D in Denmark, use of once-weekly semaglutide independently more than doubled the risk of NAION. Given the irreversible nature of NAION, it is important to acknowledge this risk, and upcoming studies should aim to identify high-risk subgroups.

International Journal of Retina and VitreousVol. 10(1)
Steno Diabetes Centers (DK), University of Southern Denmark (DK), Odense University Hospital (DK)
Good health and well-being
Openalex Percentile: Top 0%
Intraoperative Neuromonitoring and Anesthetic Effects
29.21
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