Predicted breeding values for relative scrapie susceptibility for genotyped and ungenotyped sheep
A linear model for predicting allele content for the PRNP gene, combined with estimates of relative susceptibility associated with PRNP genotypes, can provide RSS EBV for scrapie resistance for ungenotyped selection candidates with accuracy up to 0.65. These RSS EBV can complement selection strategies based on PRNP genotypes, especially in populations where resistant genotypes are rare.
Authors
- Jón H. Eiríksson (ORCID: https://orcid.org/0000-0002-4655-2850)
- Þórdís Þórarinsdóttir (ORCID: https://orcid.org/0000-0002-6520-3509)
- Egill Gautason (ORCID: https://orcid.org/0000-0002-7343-0314)
Institutions
- Agricultural University of Iceland (IS)
- Icelandic Tourism Research Centre (IS)
Publication Details
- Journal
- Genetics Selection Evolution
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12711-024-00947-x
- Primary Topic
- Prion Diseases and Protein Misfolding
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Icelandic Ministry of Fisheries and Agriculture