Fecal carriage of ESBL-producing E. coli and genetic characterization in rural children and livestock in the Somali region, Ethiopia: a one health approach
We report a high prevalence of ESBL E. coli in rural children, which outnumbers its prevalence in livestock. These isolates displayed a high diversity of sequence types (STs) with ST-2353 being the dominant ST. Our study is the first to report the association of ST-2353 with multi-drug resistance genes in Ethiopia. Further research using an integrated approach including other domains such as water and food products is needed to truly understand and combat AMR transmission and acquisition in this region.
Authors
- Rea Tschopp (ORCID: https://orcid.org/0000-0001-8435-0259)
- Jan Hattendorf (ORCID: https://orcid.org/0000-0002-1176-401X)
- Tobias Schindler (ORCID: https://orcid.org/0000-0002-5961-095X)
- Salome Hosch (ORCID: https://orcid.org/0000-0001-9290-3589)
- Ashenafi Alemu
- Guéladio Cissé (ORCID: https://orcid.org/0000-0002-6286-976X)
- Abdifatah Muktar Muhummed (ORCID: https://orcid.org/0000-0002-1966-729X)
- Yahya Osman
- Pascale Vonaesch (ORCID: https://orcid.org/0000-0002-1064-6505)
- Jakob Zinsstag (ORCID: https://orcid.org/0000-0002-8899-6097)
- Simon Yersin (ORCID: https://orcid.org/0000-0002-4694-2234)
Institutions
- Swiss Tropical and Public Health Institute (CH)
- University of Basel (CH)
- Jigjiga University (ET)
- Armauer Hansen Research Institute (ET)
- University of Lausanne (CH)
Publication Details
- Journal
- Antimicrobial Resistance and Infection Control
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13756-024-01502-5
- Citations
- 9
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.53
Funders
- Universität Basel
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Nutricia Research Foundation
- Université de Lausanne