LL-37 regulates odontogenic differentiation of dental pulp stem cells in an inflammatory microenvironment
These findings suggest that the polypeptide LL-37 facilitates the migration of DPSCs and plays a crucial role in resolving inflammation and promoting cell differentiation within an inflammatory microenvironment. Consequently, LL-37 has promising potential as an innovative therapeutic approach for managing inflammatory dental pulp conditions.
Authors
- Quanli Li (ORCID: https://orcid.org/0000-0002-3546-5663)
- Ruoxi Dai (ORCID: https://orcid.org/0000-0001-6576-3269)
- Yunfeng Ma (ORCID: https://orcid.org/0000-0002-7699-473X)
- Xinyuan Liu (ORCID: https://orcid.org/0000-0002-9754-0593)
- Ying Cao (ORCID: https://orcid.org/0000-0002-9901-1038)
Institutions
- Tufts University (US)
- Anhui Medical University (CN)
- Shenzhen Zhongshan Urological Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13287-024-04075-7
- Citations
- 3
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Anhui University
- University Natural Science Research Project of Anhui Province