Bexarotene ameliorated the pulmonary inflammation and M1 polarization of alveolar macrophages induced by cigarette smoke via PPARγ/HO-1
Our results indicated that bexarotene may curb inflammation and M1 polarization in COPD through activation of the PPARγ/HO-1 pathway.
Authors
- Rui Zheng (ORCID: https://orcid.org/0000-0001-5906-0081)
- Zhe Li (ORCID: https://orcid.org/0000-0001-7798-8983)
- Haoshen Feng
Institutions
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12931-024-03064-x
- Citations
- 8
- Primary Topic
- Eicosanoids and Hypertension Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 2.36
Funders
- Natural Science Foundation of Liaoning Province
- Shengjing Hospital