Matrix-free human lung organoids derived from induced pluripotent stem cells to model lung injury
By establishing these free-floating LuOrgs for the investigation of cancer therapeutic approaches as a new and patient-oriented in vitro platform particularly in experimental radiooncology, not only a reduction in the number of experimental animals, but also an adequately and meaningfully replacement of corresponding animal experiments can be achieved.
Authors
- Diana Klein (ORCID: https://orcid.org/0000-0002-1770-443X)
- Bettina Budeus (ORCID: https://orcid.org/0000-0002-9313-8636)
- Chiara Kroepel
- Lisa Marie Stasch
Institutions
- Essen University Hospital (DE)
- University of Duisburg-Essen (DE)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13287-024-04106-3
- Citations
- 13
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 5.45
Funders
- Universitätsklinikum Essen
- Bundesministerium für Bildung und Forschung
- Universität Duisburg-Essen