Prion protein regulates invasiveness in glioblastoma stem cells

These findings establish PrP<sup>C</sup> as a modulator of essential molecules on the cell surface of GSCs, highlighting its potential as a therapeutic target for GBM.

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Publication Details

Journal
BMC Cancer
Published
2024-12-18
DOI
https://doi.org/10.1186/s12885-024-13285-4
Citations
2
Primary Topic
Prion Diseases and Protein Misfolding
Type
article
Field-Weighted Citation Impact
0.47

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article

Prion protein regulates invasiveness in glioblastoma stem cells

Tiago G. Santos, Rebeca Piatniczka Iglesia, Camila Felix de Lima Fernandes, Maria Isabel Melo-Escobar et al.
2 citations
BMC Cancer
Prion Diseases and Protein Misfolding
0.47
article

Prion protein regulates invasiveness in glioblastoma stem cells

Tiago G. Santos, Rebeca Piatniczka Iglesia, Camila Felix de Lima Fernandes, Maria Isabel Melo-Escobar, Helder I. Nakaya, Flávio H. Beraldo, Mário Costa Cruz, Shamini Ayyadhury, Mariana Brandão Prado, Frederico Moraes Ferreira, Marco A. M. Prado, Jacqueline Marcia Boccacino, Marilene H. Lopes, Martin L. Duennwald, Rodrigo Nunes Alves, Bárbara Paranhos Coelho, Jue Fan
article en
2 citations

Abstract

These findings establish PrP<sup>C</sup> as a modulator of essential molecules on the cell surface of GSCs, highlighting its potential as a therapeutic target for GBM.

BMC CancerVol. 24(1)
Western University (CA), University Health Network (CA), Universidade de São Paulo (BR), University of Toronto (CA), Hospital Israelita Albert Einstein (BR), Princess Margaret Cancer Centre (CA), AC Camargo Hospital (BR), Institute of Biomedical Science (GB)
Fundação de Amparo à Pesquisa do Estado de São Paulo, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Natural Sciences and Engineering Research Council of Canada
Zero hunger
Openalex Percentile: Top 33%
Prion Diseases and Protein Misfolding
0.47
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