Reduced plastid genomes of colorless facultative pathogens Prototheca (Chlorophyta) are retained for membrane transport genes
The retention of vestigial genomes in colorless plastids is typically associated with the biosynthesis of secondary metabolites. In contrast, the remarkable conservation of plastid membrane transport system components in the nonphotosynthetic genera Prototheca and Helicosporidium provides an additional constraint against the loss of ptDNA in this lineage. Furthermore, these genes can potentially serve as targets for therapeutic intervention, indicating their importance beyond the evolutionary context.
Authors
- Kacper Maciszewski (ORCID: https://orcid.org/0000-0001-8556-9500)
- Anna Karnkowska (ORCID: https://orcid.org/0000-0003-3709-7873)
- Jan Gawor (ORCID: https://orcid.org/0000-0003-3800-2557)
- Robert Gromadka (ORCID: https://orcid.org/0000-0002-9941-6692)
- Tomasz Jagielski (ORCID: https://orcid.org/0000-0001-9553-5742)
- Zofia Bakuła (ORCID: https://orcid.org/0000-0001-7560-2100)
- Gabriela Wilga
Institutions
- Institute of Biochemistry and Biophysics, Polish Academy of Sciences (PL)
- Institute of Parasitology (CZ)
- Czech Academy of Sciences, Biology Centre (CZ)
- University of Warsaw (PL)
Publication Details
- Journal
- BMC Biology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12915-024-02089-4
- Citations
- 2
- Primary Topic
- Genomics and Phylogenetic Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Narodowym Centrum Nauki