An hiPSC-CM approach for electrophysiological phenotyping of a patient-specific case of short-coupled TdP
This patient-specific case of electrophysiological phenotyping resulted in a hypothesis of the possible mechanism behind the scTdP arrhythmias, but also accentuates the applicability of patient-specific hiPSC-CM disease modeling and phenotyping.
Authors
- Merel L. Ligtermoet
- Willem B. van Ham (ORCID: https://orcid.org/0000-0002-6621-148X)
- Esmeralda E. M. Meijboom (ORCID: https://orcid.org/0000-0001-8917-1460)
- Folkert W. Asselbergs (ORCID: https://orcid.org/0000-0002-1692-8669)
- Toon A.B. van Veen (ORCID: https://orcid.org/0000-0002-4775-5924)
- Jantine Monshouwer‐Kloots
- Eva van Rooij
- Mimount Bourfiss (ORCID: https://orcid.org/0000-0001-5820-4610)
- Anneline S.J.M. te Riele (ORCID: https://orcid.org/0000-0002-4694-4790)
Institutions
- Royal Netherlands Academy of Arts and Sciences (NL)
- University Medical Center Utrecht (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13287-024-04074-8
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dutch Cardiovascular Alliance
- Universitair Medisch Centrum Utrecht