Hypoxic mesenchymal stem cell-derived exosomal circDennd2a regulates granulosa cell glycolysis by interacting with LDHA
This study revealed that HM-Exs-circDennd2a promoted LDHA activity and enhanced GCs glycolytic capacity, both of which support its use as a potential clinical diagnostic and therapeutic target for POI.
Authors
- Xiaolan Zhu
- Wenxin Li (ORCID: https://orcid.org/0000-0001-6660-477X)
- Li Lin (ORCID: https://orcid.org/0000-0001-9233-948X)
- Minjun Lu
- Jiamin Zhou (ORCID: https://orcid.org/0000-0003-0223-8461)
- Junyu Shang
- Dan Zhao
- Yueqin Liu
Institutions
- Jiangsu University (CN)
- Affiliated Hospital of Jiangsu University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13287-024-04098-0
- Citations
- 8
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Jiangsu Commission of Health
- National Natural Science Foundation of China
- Jiangsu University
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- Project 333 of Jiangsu Province