Umbilical cord-derived mesenchymal stem cells preferentially modulate macrophages to alleviate pulmonary fibrosis
Therefore, UCMSCs demonstrated superior anti-fibrotic abilities in treating lung damage, potentially through inducing a more robust M2 polarization of macrophages than PLMSCs.
Authors
- Yinyin Wang (ORCID: https://orcid.org/0000-0003-1285-0507)
- Muyang Yan (ORCID: https://orcid.org/0000-0001-6978-1472)
- Meng Li (ORCID: https://orcid.org/0000-0001-5937-0709)
- Mengdi Li (ORCID: https://orcid.org/0000-0001-5605-329X)
- Zhijie Chang (ORCID: https://orcid.org/0000-0003-1567-3227)
- Guancheng Jiang
- Hanguo Jiang
- Fangli Ren (ORCID: https://orcid.org/0000-0003-1858-6989)
- Jun Li (ORCID: https://orcid.org/0009-0002-4497-9305)
- Ying Wang (ORCID: https://orcid.org/0000-0002-2571-9367)
- Ziying Zhu
Institutions
- Chinese PLA General Hospital (CN)
- State Key Laboratory of Membrane Biology
- Tsinghua University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s13287-024-04091-7
- Citations
- 7
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 2.93
Funders
- Tsinghua University