Comment on: Toward an optimal contraception dosing strategy
The optimal contraception dosing strategy proposed by Gavina et al. recently is a commendable attempt to model a complex physiological process with potenial to apply to real-life data. However, there is a need to take into account the real challenges that arise when moving from the theory to its practical application, and it is important that lessons learnt from clinical studies be taken into consideration in any theoretical modelling. In this manuscript, we spell out these lessons and elaborate practical challenges facing their model.
Authors
- Sun‐Wei Guo (ORCID: https://orcid.org/0000-0002-8511-7624)
- Giuseppe Benagiano (ORCID: https://orcid.org/0000-0002-3168-4594)
- Giovanni Grandi (ORCID: https://orcid.org/0000-0002-3567-3278)
- Marwan A Habiba (ORCID: https://orcid.org/0000-0001-5404-252X)
- Andrea R. Genazzani
Institutions
- University of Pisa (IT)
- University of Modena and Reggio Emilia (IT)
- University of Leicester (GB)
- University Hospitals of Leicester NHS Trust (GB)
- Azienda Ospedaliero-Universitaria di Modena (IT)
- Foundation for laboratory medicine (CH)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- PLoS Computational Biology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1371/journal.pcbi.1012398
- Citations
- 2
- Primary Topic
- Reproductive Health and Contraception
- Type
- article
- Field-Weighted Citation Impact
- 1.09