Analysis of Fibroblast Growth Factor 2 Impact and Mechanism on Broncho-Pulmonary Dysplasia
FGF2 was closely associated with EMT in BPD mice. Both high and low levels of FGF2 promoted EMT in A549. The FGF2 receptor inhibitor BGJ398 reversed TGF-β1-induced EMT in A549 by inhibiting the FGFR1/P-ERK signaling pathway.
Authors
- Zhenghai Qu (ORCID: https://orcid.org/0000-0002-4684-8651)
- Dongyun Liu (ORCID: https://orcid.org/0000-0001-9852-8847)
- Y. Liu
- Ling Lu (ORCID: https://orcid.org/0000-0002-6959-405X)
- Rong Jin
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1159/000543105
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00