Effect of Metformin on Meibomian Gland Epithelial Cells: Implications in Aging and Diabetic Dry Eye Disease
Our results using a cell line suggest that metformin affects the cellular physiology of meibomian gland epithelial cells and induces cell stress in a dose- and duration-dependent manner, causing changes in their morphology and ultrastructure.
Authors
- Martin Schicht (ORCID: https://orcid.org/0000-0001-5155-5477)
- Ingrid Zahn (ORCID: https://orcid.org/0000-0002-6477-4940)
- Swati Singh (ORCID: https://orcid.org/0000-0001-7420-9438)
- Friedrich Paulsen (ORCID: https://orcid.org/0000-0002-0527-0953)
- Leon Rescher
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- L V Prasad Eye Institute (IN)
Publication Details
- Journal
- Life
- Published
- 2024-12-18
- DOI
- https://doi.org/10.3390/life14121682
- Citations
- 5
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Deutsche Forschungsgemeinschaft