Integrative multi-omics analysis reveals the contribution of neoVTX genes to venom diversity of Synanceia verrucosa
The results identified the major venom composition of S. verrucosa, and highlighted the contribution of neoVTX genes to the diversity of venom composition through tandem-duplication and alternative splicing. The diverse neoVTX proteins in the venom as lethal particles are important for understanding the adaptive evolution of S. verrucosa. Further functional studies are encouraged to exploit the venom components of S. verrucosa for pharmaceutical innovation.
Authors
- Zhaojie Peng (ORCID: https://orcid.org/0000-0003-2322-3904)
- Wenliang Zhou (ORCID: https://orcid.org/0000-0002-1240-8842)
- Fuwen Wei (ORCID: https://orcid.org/0000-0002-5233-1288)
- Shichao Wei (ORCID: https://orcid.org/0000-0001-9151-1356)
- Qian Li (ORCID: https://orcid.org/0000-0001-7614-5618)
- Zhiwei Zhang (ORCID: https://orcid.org/0000-0002-0769-5007)
- Hao Li (ORCID: https://orcid.org/0000-0002-5462-8974)
- Yu Wen (ORCID: https://orcid.org/0000-0002-4413-2115)
Institutions
- Chinese Academy of Sciences (CN)
- Guangzhou University (CN)
- Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) (CN)
- Institute of Zoology (CN)
- Jiangxi Agricultural University (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12864-024-11149-6
- Citations
- 4
- Primary Topic
- Marine Invertebrate Physiology and Ecology
- Type
- article
- Field-Weighted Citation Impact
- 6.35
Funders
- National Natural Science Foundation of China
- Ministry of Science and Technology of the People's Republic of China
- Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)