Genome-wide identification and diversity of FAD2, FAD3 and FAE1 genes in terms of biotechnological importance in Camelina species

It was shown that the FAD2, FAD3 and FAE1 genes retain high conservation, even in allohexaploid C. sativa after polyploidzation, in which the subfunctionalization of the described homeologs is mainly grounded on the expressional differences. The major differences in FA accumulation patterns within the seeds of different species were identified as well. These results provide a foundation for future precise gene editing, which would be based on targeting of particular FAD2, FAD3 and FAE1 gene copies in C. sativa that allow regulating the dosage of the mentioned genes, thus shaping the desired FA composition in cultivated false flax.

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Publication Details

Journal
BMC Biotechnology
Published
2024-12-18
DOI
https://doi.org/10.1186/s12896-024-00936-4
Citations
8
Primary Topic
Lipid metabolism and biosynthesis
Type
article
Field-Weighted Citation Impact
2.36

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article

Genome-wide identification and diversity of FAD2, FAD3 and FAE1 genes in terms of biotechnological importance in Camelina species

Edgar B. Cahoon, Ya. B. Blume, Tara J. Nazarenus, R. Y. Blume et al.
8 citations
BMC Biotechnology
Lipid metabolism and biosynthesis
2.36
article

Genome-wide identification and diversity of FAD2, FAD3 and FAE1 genes in terms of biotechnological importance in Camelina species

Edgar B. Cahoon, Ya. B. Blume, Tara J. Nazarenus, R. Y. Blume, V. Y. Hotsuliak
article en
8 citations

Abstract

It was shown that the FAD2, FAD3 and FAE1 genes retain high conservation, even in allohexaploid C. sativa after polyploidzation, in which the subfunctionalization of the described homeologs is mainly grounded on the expressional differences. The major differences in FA accumulation patterns within the seeds of different species were identified as well. These results provide a foundation for future precise gene editing, which would be based on targeting of particular FAD2, FAD3 and FAE1 gene copies in C. sativa that allow regulating the dosage of the mentioned genes, thus shaping the desired FA composition in cultivated false flax.

BMC BiotechnologyVol. 24(1)
University of Nebraska–Lincoln (US), National Academy of Sciences of Ukraine (UA), Institute of Food Biotechnology and Genomics (UA)
U.S. Department of Energy, CRDF Global, National Academy of Sciences of Ukraine, National Institute of Food and Agriculture, Office of Science
Zero hunger
Openalex Percentile: Top 12%
Lipid metabolism and biosynthesis
2.36
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