Prognostic value of immuno-inflammatory biomarkers in esophageal squamous cell carcinoma patients receiving immunotherapy combined with chemoradiotherapy and its association with immuno-genomic landscape
Pre-CRT PLR, ALC nadir during CRT, and post-CRT NLR were significantly associated with PFS in patients with ESCC receiving CRT and immunotherapy. A nomogram model with good prognostic ability was developed.
Authors
- Mian Xi (ORCID: https://orcid.org/0000-0002-8088-0970)
- Baoqing Chen (ORCID: https://orcid.org/0000-0001-9807-7425)
- Ruixi Wang (ORCID: https://orcid.org/0009-0005-4056-9618)
- Xingyuan Cheng
- Qiaoqiao Li (ORCID: https://orcid.org/0000-0002-6299-4966)
- Shiliang Liu (ORCID: https://orcid.org/0000-0001-5830-5171)
- Fanjun Meng (ORCID: https://orcid.org/0000-0001-5731-1203)
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
- State Key Laboratory of Oncology in South China
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12885-024-13298-z
- Citations
- 1
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- Beijing Xisike Clinical Oncology Research Foundation
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Chinese Society of Clinical Oncology