Alleviating role of ketamine in breast cancer cell-induced osteoclastogenesis and tumor bone metastasis-induced bone cancer pain through an SRC/EGR1/CST6 axis
This study demonstrates that ketamine alleviates BC cell-induced osteoclastogenesis and tumor bone metastasis by suppressing SRC and restoring the EGR1/CST6 axis.
Authors
- Yanmei Zhang
- Xiaomin Zhang (ORCID: https://orcid.org/0000-0003-3877-5242)
- Du Wei (ORCID: https://orcid.org/0000-0003-1215-2223)
Institutions
- Liaoning Cancer Hospital & Institute (CN)
- China Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12885-024-13290-7
- Citations
- 5
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 1.93
Funders
- Natural Science Foundation of Liaoning Province