GG-NER’s role in androgen receptor signaling inhibitor response for advanced prostate cancer
NECGS effectively predicts ARSI response in PCa, and our comprehensive analysis underscores the critical role of the GG-NER pathway in enzalutamide resistance, positioning ACTL6A as a potential therapeutic target for PCa.
Authors
- J X Wang (ORCID: https://orcid.org/0000-0001-9834-6680)
- Xiangming Mao (ORCID: https://orcid.org/0000-0002-7690-0924)
- Chuanfan Zhong (ORCID: https://orcid.org/0000-0002-0824-1517)
- Zining Long
- Jianming Lü (ORCID: https://orcid.org/0000-0002-3794-641X)
- Zhongjie Chen (ORCID: https://orcid.org/0000-0002-1338-4387)
- Zhuoyuan Lin (ORCID: https://orcid.org/0000-0002-1697-6740)
- Rujun Mo
- Weibo Zhong
- Le Zhang (ORCID: https://orcid.org/0009-0008-0205-2150)
- Guo Chen (ORCID: https://orcid.org/0000-0003-4069-8311)
- Chao Cai (ORCID: https://orcid.org/0000-0001-7945-4301)
- H L Peng (ORCID: https://orcid.org/0009-0001-6763-9269)
- Shilong Cheng
Institutions
- University of California, Riverside (US)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou First People's Hospital (CN)
- Zhujiang Hospital (CN)
- Dongguan People’s Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12964-024-01977-0
- Citations
- 5
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- National Natural Science Foundation of China
- Natural Science Foundation for Young Scientists of Shanxi Province
- Young Scientists Fund
- Basic and Applied Basic Research Foundation of Guangdong Province