STING exerts antiviral innate immune response by activating pentose phosphate pathway
Our findings reveal that the PPP plays a synergistic role in generating antiviral immune factors during viral infection and suggest that PPP activation could serve as an adjunct strategy for antiviral therapy.
Authors
- Dan‐Hui Wu
- Huai Liu
- Zhenhua Yan (ORCID: https://orcid.org/0000-0002-8420-0100)
- Yong‐Ping Jian
- Lingjun Zhu (ORCID: https://orcid.org/0000-0001-8033-1528)
- Zilong Zhao (ORCID: https://orcid.org/0000-0001-8218-6395)
- Yujia Li (ORCID: https://orcid.org/0000-0002-2636-5468)
- Wei-Tao Yin
- Junqi Li (ORCID: https://orcid.org/0000-0003-3457-4099)
- Zhi–Xiang Xu (ORCID: https://orcid.org/0000-0002-6142-446X)
- Xiong-Yan Xiang (ORCID: https://orcid.org/0009-0002-1496-4073)
Institutions
- Henan University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12964-024-01983-2
- Citations
- 3
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- National Key Research and Development Program of China