Photoinduced synthesis of trisubstituted allylic molecules <i>via</i> migratory allylation of olefins
A transition-metal-free method to afford diverse trisubstituted allylic molecules <i>via</i> migratory allylation of olefins under light irradiation is described. This system tolerated diverse <i>N</i>-tosylhydrazones and olefinic boronic acids. Successful allylation of drugs and natural-product analogues was achieved. The gram-scale synthesis and subsequent post-transformation demonstrated the potential applications of this strategy.
Authors
- Weijie Wang (ORCID: https://orcid.org/0000-0002-5392-4958)
- Weidong Zhang (ORCID: https://orcid.org/0000-0002-7384-2490)
- Yu Zhang (ORCID: https://orcid.org/0000-0002-7230-3575)
- Mingdong Zhong (ORCID: https://orcid.org/0000-0002-1306-3305)
- Qiannan Li (ORCID: https://orcid.org/0000-0003-1221-9766)
- Dingding Xia
- Na Zhang (ORCID: https://orcid.org/0009-0008-8121-2633)
Institutions
- Tianjin Normal University (CN)
- Second Military Medical University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai East Hospital (CN)
- Henan Normal University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1039/d4cc05368k
- Citations
- 1
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.25