Impact of Anti-CD4 Autoantibodies on Immune Reconstitution in People With Advanced HIV
People with advanced HIV harboring anti-CD4 autoantibodies at ART initiation demonstrated a slower rate and extent of CD4 reconstitution after 4 years. Incidental immunosuppressive therapy was associated with increased CD4 counts in these participants.
Authors
- Gregg Roby
- V. Koneti Rao (ORCID: https://orcid.org/0000-0002-7881-6902)
- April Poole (ORCID: https://orcid.org/0000-0003-0767-4334)
- Stephen A. Migueles (ORCID: https://orcid.org/0000-0002-6062-8022)
- Peter D. Burbelo (ORCID: https://orcid.org/0000-0003-1717-048X)
- Elizabeth Laidlaw (ORCID: https://orcid.org/0000-0001-8241-6859)
- Ainhoa Pérez‐Díez (ORCID: https://orcid.org/0000-0001-8948-554X)
- Maura M. Manion (ORCID: https://orcid.org/0000-0003-0991-0011)
- Brian Epling (ORCID: https://orcid.org/0000-0002-7434-942X)
- Andrea Lisco (ORCID: https://orcid.org/0000-0002-1475-356X)
- Virginia Sheikh (ORCID: https://orcid.org/0000-0003-2006-7440)
- Frances Galindo
- Irini Sereti (ORCID: https://orcid.org/0000-0002-0076-0224)
- Xiangdong Liu (ORCID: https://orcid.org/0000-0002-9816-688X)
- Megan Anderson
Institutions
- National Institutes of Health (US)
- National Institute of Dental and Craniofacial Research (US)
- National Institute of Allergy and Infectious Diseases (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1093/cid/ciae562
- Citations
- 4
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Division of Intramural Research, National Institute of Allergy and Infectious Diseases
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases
- National Institute of Dental and Craniofacial Research