Multiomic Integration Analysis for Monitoring Severe Asthma Treated With Mepolizumab or Omalizumab
Our results provide a comprehensive insight into the differential effects of mepolizumab and omalizumab on the immunometabolic kinetics of the inflammatory response in severe asthma. We identified a set of biomolecules with potential for monitoring mepolizumab treatment which could be useful for personalized medicine.
Authors
- David Obeso (ORCID: https://orcid.org/0000-0001-7875-7327)
- Paloma Fernández (ORCID: https://orcid.org/0000-0001-5941-8442)
- Santiago Angulo (ORCID: https://orcid.org/0000-0002-7868-7442)
- Heleia González Cuervo (ORCID: https://orcid.org/0009-0001-6809-2410)
- Victoria Múgica (ORCID: https://orcid.org/0000-0001-5379-5642)
- María Isabel Delgado Dolset (ORCID: https://orcid.org/0000-0001-7924-5454)
- Nuria Contreras (ORCID: https://orcid.org/0000-0003-4437-6758)
- Alma Villaseñor (ORCID: https://orcid.org/0000-0002-6652-2739)
- Carlos Blanco (ORCID: https://orcid.org/0000-0002-2893-6594)
- Domingo Barber (ORCID: https://orcid.org/0000-0002-5488-5700)
- Carolina Cisneros (ORCID: https://orcid.org/0000-0003-4297-4199)
- Teresa Carrillo (ORCID: https://orcid.org/0000-0002-3047-8908)
- María Marta Escribese (ORCID: https://orcid.org/0000-0001-5057-5150)
- José Cumplido (ORCID: https://orcid.org/0000-0002-6878-9488)
- Elena Izquierdo (ORCID: https://orcid.org/0000-0002-3355-2798)
- Coral Barbas (ORCID: https://orcid.org/0000-0003-4722-491X)
- Andrea Escolar‐Peña (ORCID: https://orcid.org/0009-0008-8197-6107)
Institutions
- Universidad San Pablo CEU (ES)
- Universidad de Las Palmas de Gran Canaria (ES)
- Hospital Universitario de Gran Canaria Doctor Negrín (ES)
- Hospital Universitario de La Princesa (ES)
Publication Details
- Journal
- Allergy
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1111/all.16434
- Citations
- 6
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.96
Funders
- Fundación Mutua Madrileña
- Comunidad de Madrid
- Universidad de Las Palmas de Gran Canaria
- Instituto de Salud Carlos III